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Biotest AG (BIO3.DE)

Dr. Christoph Uherek

Head of Preclinical Development

Germany

Biotest AG: BT-062 - A Potent Antibody-Drug Conjugate for the Treatment of CD138 Expressing Tumors

BT-062 is an antibody-drug conjugate binding to CD138, which is over-expressed on multiple myeloma (MM) and a variety of solid tumors. BT-062 has shown good tolerability in clinical phase I/II studies and achieved clinical benefit in MM patients. Additionally, BT-062 demonstrated very good efficacy in solid tumor animal models (e.g. triple negative breast cancer), making it a promising candidate for development in solid tumor indications.


Please select the appropriate option to comply with legal regulations

Individual Investor

This multimedia channel includes general category videos, webcasts and live broadcasts suitable for members of the public over 18 years of age and not engaged in providing investment advice. Access this channel for personal interest and information only.

Professional Investor or Financial Advisor

This multimedia channel includes investor videos and webcast presentations, live broadcasts and documents intended only for authorised and regulated professional investors and financial advisers eligible to provide investment advice to private investors.

Enter Media Channel

No reliance should be placed on the information on this site which may change without notice.
You should read the Terms & Conditions section before browsing this site.

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00:00
Biotest AG, BT-062: A Potent Antibody-Drug Conjugate for the Treatment of CD138 Expressing Tumors
00:15
Biotest Group, Headquarters, Subsidiaries, Employees, Biotest shares, Financials, Biotest Group
00:55
Plasma Proteins, Biotherapeutics, Immunoglobulins, Hyper- Immunoglobulins, Clotting factors, Human Albumin, Monoclonal Antibodies, BT 061, BT 062, BT 063, Clinical Development, Production at BPC, License Agreement , Biotest: a specialized pharmaceutical company
02:05
Multiple Myeloma, Forecast, hematologic malignancy , Multiple Myeloma: Overview
03:00
Myeloma Current Treatment, Stem cell transplant candidates, Thalidomide, dexamethasone 1, Velcade, dexamethasone, Velcade, doxorubicin, dexamethasone, Thalomid, Velcade, liposomal doxorubicin, Revlimid, dexamethasone, Drugs in clinical development , Multiple Myeloma: Current Treatment Overview
04:00
Efficacy Issues, drug toxicities, multiple myeloma, The Most Significant Unmet Needs in Multiple Myeloma Arise from Safety and Efficacy Issues
04:34
Multiple Myeloma Market, Novel Agents, Revlimid, Velcade, Thalomid, Multiple Myeloma Market (7MM)1 - Growth Driven by Increased Uptake of 'Novel Agents'
06:00
BT-062 Market Opportunity, Relapsed, Refractory, BT-062 , BT-062 Market Opportunity in Relapsed, Refractory Multiple Myeloma
06:22
potent Antibody-Drug Conjugate, Multiple Myeloma, Tumor-targeting, CD138, BT-062: A potent Antibody-Drug Conjugate for Treatment of Multiple Myeloma
07:53
BT-062, Mode of Action, Binding, Internalization, Binding to CD138, Receptor, polymerization , BT-062: Mode of Action
08:58
Conjugate Optimization, Efficacy, BT-062-mediated, Xenograft model, toxin-linker, BT-062: Improved Efficacy after Conjugate Optimization
10:45
Clinical Development, Monotherapy, Revlimid, Result , BT-062: Clinical Development in Multiple Myeloma
11:54
Study 969, Clinical Benefit, Monotherapy Study, , Study 969: Clinical Benefit Shown in a Dose Finding Phase I Multiple Myeloma Monotherapy Study
12:58
serum FLC, oligo-secretory Multiple Myeloma, , BT-062: Repeated Single Dose Study 969
13:50
Intensification of Exposure, Phase I/IIa, monotherapy, , Study 975: Intensification of Exposure by More Frequent Dosing - Study Ongoing
14:29
Rationale for Clinical Development, Solid Tumor Indications, CD138 expression, mammary, prostate, lung, head and neck, bladder, and pancreatic carcinoma, clinical study, BT-062: Rationale for Clinical Development in Solid Tumor Indications
15:06
BT-062 in Solid Tumor Indications, remission, carcinoma xenograft, HER2-negative, triple negative breast cancer, BT-062 in Solid Tumor Indications
16:10
BT-062: Development Plan and Milestones, Mono therapy, Combination therapy, Efficacy, BT-062: Development Plan and Milestones