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WILEX AG (WL6)

Prof. Dr. Olaf G. Wilhelm

Chief Executive Officer

Germany

WILEX AG - Research and development of smallmolecule drugs for autoimmune diseases and cancer

The therapeutic agent RENCAREX® (INN: Girentuximab) is a targeted antibody for the treatment of solid tumours. The antibody Girentuximab binds to the CA IX antigen expressed on the tumour cells, thereby triggering an immune reaction called Antibody-Dependent Cellular Cytotoxicity (ADCC). Through this mechanism, effector cells, e.g. NK (natural killer) cells, of the immune system are activated to kill the tumour cells.


Please select the appropriate option to comply with legal regulations

Individual Investor

This multimedia channel includes general category videos, webcasts and live broadcasts suitable for members of the public over 18 years of age and not engaged in providing investment advice. Access this channel for personal interest and information only.

Professional Investor or Financial Advisor

This multimedia channel includes investor videos and webcast presentations, live broadcasts and documents intended only for authorised and regulated professional investors and financial advisers eligible to provide investment advice to private investors.

Enter Media Channel

No reliance should be placed on the information on this site which may change without notice.
You should read the Terms & Conditions section before browsing this site.

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00:00
WILEX AG, Guiding targeted therapies through diagnostics
00:10
sales, Deals, Alliances, Oncology-focused biopharmaceutical, clinical and commercial milestones, combination of therapeutics and diagnostics, Products Technologies , At a glance
00:50
portfolio, partners, REDECTANE®, RENCAREX®, MESUPRON®, WX-554, WX-037, Antibodies, ADC Platform , Broad portfolio and strong partners
02:25
commercialisation strategy, Therapeutics, Diagnostics, Research, Royalties, Licensing, Revenues, Licensing, income, Positioning in three segments
03:10
personalised cancer treatment, CA IX, therapeutics, diagnostics, Oncogene Science , WILEX Group's combined offering
04:23
Carbonic Anhydrase IX (CAIX), HIF-1, biomarker, hypoxia, What is Carbonic Anhydrase IX (CAIX) and what does it do?
05:05
Diagnostic imaging , Diagnostic imaging
05:15
REDECTANE®, renal cell cancer (ccRCC), , REDECTANE (R): Diagnosis of clear cell renal cell cancer (ccRCC)
06:18
Girentuximab (cG250), Nijmegen, MSKCC/LICR, SPA approved by FDA , Development of the REDECTANE (R) concept
07:25
metastases, metastasis, REDECTANE (R) detects primary tumour and distant metastases
08:20
REDECTANE(R) detects also small tumours: T1a (1.7cm) ccRCC , REDECTANE(R) detects also small tumours: T1a (1.7cm) ccRCC
08:54
Final study results, REDECTANE (R): Final study results
09:27
In-vitro diagnostic , In-vitro diagnostic
09:35
Univariate analysis of biomarker in trastuzumab-treated MBC, Univariate Analysis, HER2, TIMP-1, uPA, Endoglin, CAIX, VEGF, Serum Biomarker, (PFS) p-value, (OS) p-value , Univariate analysis of biomarker in trastuzumab-treated MBC
10:35
pretreatment serum CAIX, Probability, Serum CAIX , Elevated pretreatment serum CAIX predicts reduced survival
10:59
Multivariate analysis, biomarker in trastuzumab-treated MBC, Progression-Free Survival (PFS), Conclusions , Multivariate analysis of biomarker in trastuzumab-treated MBC
11:40
oncological biomarker, personalised medicine, kidney, cervix, lung, bladder, colon and head & neck , CAIX: important oncological biomarker in the development of personalised medicine
12:20
Forward looking statements , Forward Looking Statements